Nitric Oxide Loss Declines with Age Chart


The earliest indicator of aging is the loss of Nitric Oxide production. This loss dramatically increases with age. In men, the decline of NO production starts at age 22 and rapidly increases. In women, the decline of NO production starts at age 25. By age 40, there is a nearly 50% loss of production rapidly diminishing until age 65 where there is an 85% loss of NO production. The loss of NO production rapidly accelerates the aging and quality of your skin. Scientific research has proven that Nitric Oxide improves blood flow. Nitric Oxide affects the endothelium, or the cells that line the interior surface of your microvascular blood vessels of your skin. Nitric Oxide dilates the skin’s microvascular blood vessels to allow more blood, oxygen and healing nutrients to flow to the skin.

N1 O1 is the World’s First Generational  Nitric Oxide Skincare Serum.

Visible fine lines and wrinkles start in your 20’s

Start using N1 O1 one time daily in your 20’s to give your skin what it’s missing. The best time to start using Pneuma is before fine lines and wrinkles begin to form. Increased NO production on the skin may improve the clarity, tone, quality, and texture of the skin. Pneuma users tell us that using Pneuma before their other favorite beauty products makes all their skincare and beauty products work better.

Your body only produces half of what it needs by age 40.

By age 40, your body produces only 50% of what it needs to maintain youthful skin and 15% by age 65. Most people already show the appearance of fine lines and wrinkles. Using N1 O1 once or twice daily, depending on age and the condition of your skin, will not only slow the appearance of fine lines and wrinkles, but improve your skin’s clarity, tone, and texture.

Use N1 O1 at any age to address damaged & aging skin

Dermatologists, plastic surgeons, and skincare professionals recommend and use N1 O1 for their patients. Some professionals recommend using N1 O1 twice daily to address the appearance of blemished, damaged, or aging skin. *Decline in NO production chart: Gerhard et al Hypertension 1996, Celemajer et at JACC 1994, Taddei et al Hypertension 2001, Egashiraet al Circulation 1993.